- - - Starting with the basics - - -
What is Aging?  A video Explanation  Where the science is today  What Are Epigenetic Clocks

The Clinical Trial Process   Longevity Has a Branding Problem  They Were WRONG About the Big Bang

- - - Articles and videos featuring Life Extension news! - - -

11/10/24 - Extracellular Vesicles for Treating Arthritis - Restores senescent cells instead of killing them

11/4/24 - Ketogenic Diet Effective Against Multiple Sclerosis in Mice

10/25/24 - AFAR-How Realistic is a 100-Year Life Expectancy and Why Does it Matter?

10/21/24 - Long-Term Administration of Nicotinamide Mononucleotide Mitigates High-fat-diet-induced Physiological Decline in aging mice

10/17/24 - Video: Leading Longevity Scientist Predicts Dramatic Life Extension by 2035 - Aubrey de Grey

10/16/24 - Tolerance Bio launches to boost human healthspan via the thymus

10/11/24 - Study finds genetics shape caloric restriction’s impact on lifespan

9/26/24 - Lisnom Health launches spinal cord transplant therapy

9/20/24 - Highlighting the nature of epigenetic aging

9/12/24 - You may live longer, but will you live better?

9/5/24 - Researchers target ‘drug free life’ for rheumatoid arthritis patients

9/2/24 - Leading cardiologist suggests weight loss drugs like Ozempic may slow aging

8/27/24 - Researchers discover protein that prevents DNA damage

8/15/24 - Aging dominated by two periods of rapid change, research finds

8/12/24 - 3D printing technique brings artificial organs a step closer

8/9/24 - Neuron-specific partial reprogramming could combat cognitive decline

8/5/24 - Vegan Diet Lowers Biological Age in a New Study. Age acceleration was decreased according to multiple well-known clocks

8/2/24 - Rapamycin + Trametinib Increase Mouse Lifespan by up to 35% and reduces the growth of cancerous tumors.

7/28/24 - Emerging role of Metformin in Alzheimer’s disease: A translational view

7/26/24 - BioViva’s CEO Liz Parrish on de-risking regulatory systems and creating evidence-based medicine from medical tourism

7/22/24 - UK’s House of Lords: “By becoming the first country to treat ageing as a medical condition, we can chart a course for more effective interventions and improved health outcomes.”

7/13/24 - Precision Nutrition Improves Life Quality for Older People. Adhering to a healthy diet provides benefits as well.

7/6/24 - Gene-based therapy may be an answer to long-sought treatment for the rare disease... Timothy syndrome

7/1/24 - Blockbuster weight-loss drugs are revealing how appetite, pleasure and addiction work in the brain

6/27/24 - Podcast - AI For Longevity Drug Discovery: Breakthrough and Challenges

6/17/24 - A Natural Compound as an Osteoporosis Treatment -It has been previously investigated for its effects on aging

6/14/24 - Mix of Lifestyle Interventions Might Reverse Alzheimer’s

6/10/24 - Transplantation of Young Bone Marrow Improves Symptoms in a Mouse Model of Alzheimer's Disease

6/4/24 - Breakthrough Discovery in Telomere Maintenance Mechanism Sheds Light on Cancer and Genetic Disorders

5/27/24 - How exercise might help prevent DNA damage, age-related vascular issues

5/24/24 - New gene therapies produce hope and questions for patients with sickle cell disease

5/16/24 - Follistatin, Gene Therapy, Muscle Mass, and Longevity

5/14/24 - Morphoceutical's mission to create a new field of bioelectromics with ‘extraordinary’ regenerative potential.

5/12/24 -  Podcast: GEN editors celebrated DNA Day by sharing some stories about their favorite observations and applications of DNA research

5/9/24 - Human with Neuralink brain chip sees improvement after initial malfunction

5/3/24 - Time-Restricted Eating (Eating 12–8pm) More Effective for Weight Loss and Glycaemic Control than Calorie Restriction

5/1/24 - Of Yeast and Men: Longevity and Sirtuins helping us build inroads into the ravages of aging

4/29/24 - New research looks at the impact of calorie restriction on telomere length, shedding light on the complex relationship between diet and aging

4/26/24 - Repair Bio’s cholesterol-degrading platform is gearing up for clinical trials in atherosclerosis

4/25/24 - Who hosts the best shows on life extension? Check out these top longevity podcasts to usher you into a world without aging.

4/23/24 - How to Reverse Alzheimer’s Disease Dr. Heather Sanderson shares a groundbreaking narrative of hope and renewal.

4/22/24 - 6 Recently Approved Cell & Gene Therapies—And Why They Matter

4/15/24 - New study shows that exercise decreases levels of a specific fat that accumulates in our tissues as we age.

4/14/24 - Addressing inflammaging proactively can mitigate its impact on healthspan

4/12/24 - Gene Therapy Well Tolerated in Wet AMD, Shows Promise in Visual Acuity

4/11/24 - Scientists Found a Way to Supercharge Cancer-Fighting Cells

4/10/24 - Founders Forum and Longevity Technology join forces to accelerate longevity investment

4/5/24 - Andrew Scott on why humanity must pursue an ‘evergreen’ agenda to become a longevity society, rather than an aging one

4/5/24 - Hacking Healthspan: Gene Therapy and Your Telomeres from BioViva

4/4/24 - Video: Dr. Robert Lufkin on Longevity Escape Velocity with Dr. Peter Diamandis

4/4/24 - The top anti-aging groups on Facebook to keep current on life extension research.

4/3/24 - Video: Elizabeth Parrish on taking gene therapies to reverse age | Shoma Chaudhury at SYNAPSE 2024

4/2/24 - NTT DATA is tackling dementia with AI and digital avatars, hoping to improve ability and safety for those experiencing cognitive decline

3/28/24 - Video: Supplement Secrets for a Longer Lifespan with Sandra Kaufman MD

3/25/24 - Video: Synapse Conclave speakers discuss the perfect balance of human and artificial intelligence

3/20/24 - Editor of new book on the science of aging believes the key breakthroughs may yet come from ‘outliers’ in the field

3/14/24 - They want to give everyone a new thymus to reboot their immune system

3/11/24 - Video: Longevity Science 2024: New Insights on "The Hallmarks of Aging" & What They Mean

3/9/24 - Liz Parrish... Beyond Limitless: Unveiling the Real NZT-48, Klotho Gene Therapy

3/7/24 - A new study highlights the inability of most animal models to accurately translate features of female aging.

3/4/24 - Unlocking longevity: the role of telomeres and its targeting

2/26/24 - Single-dose gene therapy may stop deadly brain disorders in their tracks

2/25/24 - The Latest in Rapamycin Research on Humans. Rapamycin and its analogs do not have many large effects on people.

2/24/24 - Fasting-Mimicking Diet Might Extend Lifespan in Humans. It appears to aid a fundamental part of the immune system

2/19/24 - Gene therapy hailed as ‘medical magic wand’ for hereditary swelling disorder

2/18/24 - Phys.org's post about Using computer-engineered DNA to study cell identities

2/12/24 - Potential ‘longevity vitamin’ demonstrated positive impact on cognitive function, memory and sleep.

2/5/24 - New Combination Therapy Eradicates Cancer in Mice... Senescent cancer cells convince the immune system not to attack.

1/30/24 - Gut health could hold the key to improving cognition, immunity and healthy aging.

1/29/24 - Healthy eating and activity reverse aging marker in kids with obesity

1/26/24 - CAR T Therapy Lowers Senescence, Improves Health in Mice

1/24/24 - ‘Skinny jabs’ may be longevity drugs, but healthy people shouldn’t be taking them

1/22/24 - The Landscape of Longevity in 2024 podcast with the visionary Dr. Aubrey de Grey

1/17/24 - Texas-based biotech Enzolytics and AI Lab become a partnership aimed at advancing the fields of organ regeneration and longevity.

1/16/24 - BioViva Aims to Improve Human Longevity By Erick Mitchell

1/15/24 - Enhanced CAR T Cells Eradicate Multiple Cancers. These cells were protected against a hazardous environment.

1/13/24 - Gene Therapy Approvals Expected to Ramp Up in 2024 Amid Manufacturing, Cost Challenges

1/7/24 - An Exercise-Related Protein May Protect the Heart - This protein notably decreases inflammation in cells

1/2/24 - Therapeutic plasma exchange – a new therapeutic modality for longevity

12/28/23 - Longivity Technology takes a look at some of 2023’s longevity news

12/23/23 - Longevity explorer Bryan Johnson looks forward to humanity’s next evolutionary chapter

12/19/23 - David Sinclair Presents His Information Theory of Aging. - Restoring the epigenome may be the key to reversing aging

12/18/23 - Estée Lauder doubles down on longevity science for skincare

12/13/23 - A Seaweed Supplement May Help Prevent Muscle Loss - The molecular mechanism has not been fully explained.

12/9/23 - The role of cellular senescence in metabolic diseases and the potential for senotherapeutic interventions

12/6/23 - NIH-funded longevity study shows astaxanthin extends lifespan

11/30/23 - Healthy Diet Linked to Massive Gains in Life Expectancy

11/23/23 - American Heart Association’s ‘Life’s Essential 8’ Checklist Holds Potential for Slowing the Aging Process

11/19/23 - Mid-old cells are a potential target for anti-aging interventions in the elderly

11/14/23 - Gene Therapy for Interstellar Travel- Liz Parrish

11/6/23 - Going for gold: new International Roundtable aims to set gold standard for longevity clinics

11/4/23 - Alcohol Consumption Increases Epigenetic Age Acceleration. Binge drinking was found to be particularly harmful.

11/2/23 - One million volunteers join UK’s largest health research program

10/29/23 - Intermittent Fasting Partially Offsets Alzheimer’s in Mice... Some gene expressions were completely restored

10/25/23 - Breaking Brain Cancer Barriers: New Gene Therapy Effectively Targets Glioblastoma

10/22/23 - Dr. Jean Hebert: Progressive Brain Tissue Replacement and How we Beat Aging!

10/20/23 - The several ways to authentically cure Alzheimer’s dementia

10/11/23 - New research identifies six chemical cocktails that could reverse transcriptomic age.

10/10/23 - MAYO CLINIC IS TESTING FISETIN AS A SENESCENT CELL THERAPY

10/9/23 - LifeSpans's REJUVENATION ROADMAP Updated: October 9, 2023

10/8/23 - Video - BioViva's Liz Parrish speaking at RADDFest 2023

10/4/23 - Promising gene therapy delivers treatment directly to brain

9/26/23 - Human Clinical Trials of NMN for Safety and Effectiveness Current trials point toward NMN safety!

9/19/23 - A Potential Exercise Mimetic to Restore Youthful Memory- This factor can be injected to restore cognition in animals

9/18/23 - Video - Human Dementia Study reviewed by Integrated Health Systems', Dr. Patrick Sewell

9/17/23 - Klotho and The Thread of Life from BioViva Science

9/15/23 - Rejuvenation Technologies is targeting longevity and age-related disease with telomerase-based mRNA therapies.

9/12/23 - Ending Age-Related Diseases 2023: Conference Opening video for Longevity/DeSci Success

9/9/23 - A Metformin and Galantamine Combination for Sarcopenia had effects that neither drug had alone.

9/8/23 - Nicotinamide mononucleotide (NMN): Benefits and Side Effects

9/7/23 - Impact of Plant-Based Diets on Biological Aging. Clear differences between healthy and unhealthy plant-based foods

9/6/23 - Inflammation discovery could slow aging, prevent age-related diseases

9/2/23 - Transferring Longevity DNA Across Species: Gene from Naked Mole Rat Extends Mouse Lifespan

9/1/23 - Is Immortality Possible or Is Aging Inevitable? Some animals don't age; we may do likewise.

9/1/23 - Fisetin supplement : Benefits, Side Effects, and Research

8/31/23 - The longevity secrets of Singapore, the 6th blue zone city where people are living the longest, happiest lives

8/29/23 - Bayer-owned company says plans are now in progress for a Phase 2 Parkinson’s trial, set to begin in 2024

8/27/23 - Diversity in Daily Activities Might Slow Cognitive Decline. Even among people with low step counts.

8/27/23 - Could Insulin Nasal Spray Help Treat Alzheimer’s Symptoms?

8/26/23 - Do long-lived flies hold the key to extending human longevity?

8/23/23 - Promising Phase 1/2 Data Released on Rett Syndrome Gene Therapy Agent TSHA-102

8/21/23 - There are 4 things you can do today to scientifically reduce your body's biological age

8/19/23 - New Insights Into The Anti-Aging Properties Of Klotho

8/15/23 - Extracellular Vesicles from Stem Cells Reverse Senescence. Tiny RNA fragments seem to be the key.

8/15/23 - Restoring Helper Cell Function to Fight Alzheimer’s. Microglia naturally constrict amyloid beta plaques.

8/14/23 - The Revolutionary Potential of Human Organs on a Microchip

8/14/23 - Circadian regulation in aging: Implications for spaceflight and life on earth

8/12/23 - Tubular lysosome induction couples animal starvation to healthy aging

8/9/23- The Inflammatory Pathway to Brain Damage. Blocking this pathway appears to protect neurons.

8/7/23 - Novel vaccine may hold key to prevent or reduce the impact of Alzheimer’s disease

8/1/23 - Genetically Engineering Cells to Respond to Electricity. This approach may revolutionize drug delivery.

7/31/23 - Young Brain Cells Outcompete Old Cells in a Mouse Model - The presence of the old cells triggered reactions.

7/29/23 - Neil Riordan new book on the Rising Tide of Stem Cell Therapies

7/26/23 - Some Age-Related Gene Expression Changes May Extend Life to reflect evolutionary life extension

7/24/23 - Dr. David Sinclair Has Rejuvenated Cells Using Small Molecules

7/20/23 - Regenerative medicine has come a long way, baby! by Eve Herold

7/17/23 - Making Genetically Engineered Stem Cells Viable - Growing and selection are crucial.

7/15/23 - Developing a Recellularization Approach to Produce Thymic Tissue

7/13/23 - NEW STUDY: Discovery of Chemical Means to Reverse Aging and Restore Cellular Function

7/9/23 - Chemically induced reprogramming to reverse cellular aging from Aging US

7/6/23 - U.S. Food and Drug Administration (FDA) announced full approval for Leqembi for the treatment of Alzheimer’s disease.

7/2/23 - Critical genes for type 1 diabetes identified for first time

6/30/23 - ‘One-and-done’ CRISPR gene therapy treatment could be lifetime cure for high cholesterol — but the FDA remains cautious

6/29/23 - FDA Approves First Cellular Therapy to Treat Patients with Type 1 Diabetes

6/28/23 - FDA Approves First Gene Therapy Treatment for Duchenne Muscular Dystrophy Developed at the Abigail Wexner Research Institute

6/27/23 - Preserved Kidneys Rewarmed and Transplanted in Rats

6/26/23 - IL-17 Protein: A Key Player in Skin Aging and Potential Therapeutic Target

6/24/23 - Critical genes for type 1 diabetes identified for first time

6/23/23 - Bodybuilding Helps Older People Stay Strong in Human Study - The average age was slightly over 60.

6/21/23 - Zuzalu: Shining City on the Black Mountain - Longevity, crypto, and new ideas for societies were part of the proceedings.

6/19/23 - Niklas Anzinger on Building a New Regulatory World Communities can approach regulation in a different way

6/16/23 - Researchers discover a potential cause of Parkinson’s disease

6/14/23 - Whole-genome methylation analysis of aging human tissues identifies age-related changes in developmental and neurological pathways

6/12/23 - SENS Research Foundation’s CEO on Accelerating Rejuvenation - SRF is advancing new educational initiatives

6/10/23 - Thanatotranscriptome: genes actively expressed after organismal death

6/8/23 - How Donated Stem Cells Become Functional Cells. Certain stem cells affect their own niche.

6/5/23 - This Longevity Study Across 5 Species Found a New Pathway to Reverse Aging

6/2/23 - New potential drug target for Alzheimer’s disease identified

5/31/23 - Longevity enthusiasts want to create their own independent state. They’re eyeing Rhode Island.

5/27/23 - Collaboration trumps competition: Building a strong longevity investment ecosystem together

5/24/23 - FDA clears Elon Musk’s brain implants for human trials

5/20/23 - Allegany County boy becomes first in the world to receive special gene therapy after FDA approval

5/18/23 - Longevity is like oxygen – Aviv puts hyperbaric oxygen therapy in the spotlight to enhance healthspan

5/15/23 - Elizabeth Parrish - Gene therapy for anti-aging: effect, cost and applicable population

5/12/23 - Nurturing the Next Generation of Leaders in Aging Biology Podcast

5/9/23 - Longevity Technology... Does SIRT6 hold the key to human longevity?

5/7/23 - Video: Powering the complexity of life with Michael Levin and Nick Lane

5/4/23 - Happy worms have healthy eggs. Study hints that antidepressants could help slow reproductive aging

5/1/23 - Electric Fields Disrupt Cancer Cell Division to prolong survival and augment current therapies.

4/30/23 - Experimental Gene Therapy Increases Lifespan Of Mice By 41 Percent In Telomere Lengthening Study

4/28/23 - Video: Joao Pedro de Magalhaes | The Scientific Quest for Immortality

4/27/23 - Video: Is Aging Reversible? A Scientific Look with David Sinclair | David Sinclair | TEDxBoston

4/26/23 - Gene therapy allows teen to see snowflakes for the first time

4/25/23 - AI-Predicted mTOR Inhibitor Reduces Cancer Cell Proliferation and Extends the Lifespan of C. elegans

4/21/23 - Sirtuins, resveratrol and the intertwining cellular pathways connecting them

4/17/23 - Study of green tea and other molecules uncovers new therapeutic strategy for Alzheimer’s

4/15/23 - People with healthy gut bacteria appear more likely to live a very long time

4/10/23 - Gene therapy could be the key to longer lives. Some longevity fanatics, are taking matters into their own hands.

4/3/23 -  Daily Step Count, Less Mortality, Diminishing Returns. Physical activity is beneficial but has limits.

4/2/23 - Young Blood for Brain Boosting. Gene expression was significantly affected.

4/1/23 - Using AI to Measure Age Through the Eyes. Retinal imaging and AI have created a highly correlated biomarker.

3/31/23 - A decade of research expands the Hallmarks of Aging from nine to twelve

3/28/23 - Longevity Venture Partners raises $30m to advance aging-in-place and longevity solutions

3/23/23 - Protein with anti-aging action combats inflammation and avoids death of neurons

3/17/23 - Inflammation Strongly Predicts Mortality After Statin Use - Most of the people in this analysis were diabetic.

3/14/23 - Prof. George Church on Cellular Reprogramming and Longevity

3/9/23 - Anti-ageing gene injections could rewind your heart age by 10 years

3/7/23 - Gene Therapy Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice

3/5/23 -  Interactive charts to show the averages of both lifespan and healthspan for many countries and locales around the world

3/4/23 - When 65 is Young: The Politics of Life Extension The Political, Economic, and Cultural Implications of Radical Longevity

3/3/23 - Every 500 additional steps taken daily associated with lower heart risk

3/1/23 - The Future of Aging: A video discussion by DW Documentary from Germany

2/28/23 - From mitochondria to cells to humans: Targeting bioenergetics in aging and disease

2/26/23 Extending Health Spans By Extending Telomeres: Forbes Profile Of Liz Parrish

2/22/23 - Two U.S. congressmen have announced the formation of a bipartisan Congressional Caucus for Longevity Science.

2/19/23 - The Science of Living Forever (or a Really, Really Long Time) by Robert Roy Britt

2/15/23 - Anti-ageing scientists extend lifespan of oldest living lab rat

2/5/23 - Ultrasound Rejuvenates Senescent Cells Through Autophagy in mice.

2/4/23 - Telocyte’s gene therapy funded through to clinical trials

2/3/23 - A Light-Sensitive Drug to Remove Senescent Cells under specific conditions

1/31/23 - Global longevity investment hit $5.2 billion in 2022. Longevity is out-trending biotech and fintech.

1/18/23 - Hypertension drug could be repurposed to delay ageing, study finds

1/27/23 - Researchers identify small molecule that restores visual function after optic nerve injury

1/26/23 - Review: Best Choice Medicine's Petition for faster access to new medicine and biotechnology

1/25/23 - Researchers demonstrate that animals treated with rilmenidine have increased lifespan and improved health markers.

1/20/23 - Nature Neuroscience: Blood-to-brain communication in aging and rejuvenation

1/19/23 - Functional T cells are capable of supernumerary cell division and longevity

1/1/23 - Video - Why Aging is a Disease With David Sinclair

1/17/23 - The genomes of 23 remarkably long-lived fish species, including Rockfish, shows two metabolic pathways associated with longevity.

1/16/23 - First AI-Discovered Drug has positive results in Phase 1 Trials

1/15/23 - Scientists Created World’s First ‘Living Robots’ That Can Reproduce

1/14/23 - Scientists Have Reached a Key Milestone in Learning How to Reverse Aging

1/14/23 - Two research teams reverse signs of aging in mice

1/13/23 - FDA no longer needs to require animal tests before human drug trials

1/12/23 - Video - A novel cyclodextrin platform is tacking bad guy cells and reinvigorating them to be guardians of the immune system.

1/11/22 - The Hill: Why classifying aging as a disease could speed FDA drug approvals

1/10/23 - Lex Fridman Podcast: Michael Levin on Biology, Life, Aliens, Evolution, Embryogenesis & Xenobots

1/9/23 - NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health

1/6/23 - Longevity News... Drinking your way to longevity!

1/4/23 - Tech billionaires funding research to help us live longer and healthier lives

1/2/23 - Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

12/29/22 - Transplanting rejuvenated blood stem cells extends lifespan of aged immunocompromised mice

12/16/22 - Innovative cancer treatment device has longevity potential

12/12/22 - Clearing Out Senescent Cells Rejuvenates Human Skin The cells regained many of their lost capabilities

12/4/22 - Alcohol and the Aging Process. Medically Reviewed by Melinda Ratini, MS, DO

12/2/22 - What Happens When Everyone Realizes We Can Live Much Longer? We May Find Out As Soon As 2025

11/25/22 - Cut and paste for longevity – new CRISPR tool enables drag-and-drop gene insertion

11/20/22 - The FDA to restrict the sale of NMN as a supplement. This announcement comes as a shock to many supplement enthusiasts

11/12/22 - Quantum Healthy Longevity Innovation Mission, a new UK-based initiative touting a multi-pronged approach for longer lifespans and healthspans.

11/8/22 - Gene Therapy Sees Children With Rare Genetic Condition Walk And Talk For First Time

10/31/22 - Turn.bio Announces Preliminary Results of a CAR-T Cell Study. Working towards perfecting cellular reprogramming

10/30/22 - New Compounds Beat Resveratrol in Sirtuin Activation. Manipulating molecular structures has provided tangible results.

10/26/22 - Buck Institute for Research on Aging podcast: Steve Austad: Why do we age?

10/23/22 - Longevity breakthrough as scientists discover how to reverse aging in skeletal muscle

10/21/22 - Novel gene therapy could help children with rare genetic condition walk and talk.

10/17/22 - NEW TECH FOR GENE THERAPY COULD ADVANCE LONGEVITY!

10/15/22 - The TAME Trial - Targeting the Biology of Aging. Ushering a New Era of Interventions.

10/11/22 - Post-mortem brains of SuperAgers reveal significantly larger neurons in memory region

10/8/22 - Why Biomarkers of Biological Age Could Be Misleading

10/5/22 - Dr Robert Lufkin says "It’s time to tackle the longevity lie."

9/30/22 - In the search for eternal youth, fecal transplants may seem like an unlikely way to reverse the ageing process

9/29/22 - Mayo Clinic director on how progress in biomanufacturing is key to ensuring regenerative medicine is available to all

9/25/22 - Rob Signer video... Preventing accumulation of misfolded proteins and stress may be key to keeping stem cells fit.

9/23/22 - David Sinclair video... Should Aging Be Called A Disease? Is aging a disease? Why it matters

9/20/22 - T Cells Ward Off Aging With Help From Their Friends - Immune cells deliver packages of telomeres to T cells

9/18/22 - CRISPR cure for high cholesterol enters first human trial in New Zealand

9/16/22 - Three possible ways of turning back the clocks of ageing by Andrew Steele PhD in physics University of Oxford.

9/14/22 - Mitochondrial Division Promotes Muscle Regeneration -Mitochondrial dysfunction and stem cell exhaustion are linked.

9/12/22 - "The Zombie Problem Happening Inside You" a short video to explain aging and how to attack it.

9/8/22 - Mehmood Khan, Hevolution CEO, Talks about spending $1 billion a year on longevity. Part-1 Part-2

9/5/22 - Researchers Propose Five New Hallmarks of Aging that would expand a well-respected model of aging.

9/1/22 - Plasma Dilution Appears to Rejuvenate Humans. The approach is well-established for several diseases.

8/31/22 - Crustacean leg regeneration restores complex microanatomy and cell diversity

8/30/22 - Type 2 diabetes: New study identifies 40 more genes linked to the disease

8/27/22 - Distinct designer diamines promote mitophagy, and enhance healthspan in C. elegans and protect human cells against oxidative damage

8/24/22 - Bioprinting for bone repair improved with gene therapy

8/22/22 - Artificial Sweeteners affect intestinal bacterial communities, with some reducing the body’s ability to regulate blood glucose levels, this study finds.

8/21/22 - Video - The Science Behind Why We Age with Dr. David Sinclair

8/19/22 - 'Zombie Cells' Are Still Alive but Can't Function, and They Accumulate as We Age

8/17/22 - Intranasal Gene Therapy for Dementia Demonstrates Cognitive Benefits

8/12/22 - 7 scientifically proven ways to combat brain fog and increase cellular energy

8/7/22 - Neurons Damaged in Dementia Recognize Interruptions to Patterns

8/4/22 - Life-long dietary restrictions have negligible or damaging effects on late-life cognitive performance: A key role for genetics in outcomes

8/3/22 - Taurine supplements could be the key to reversing the aging process

7/30/22 - Young brain fluid improves memory in old mice. A protein in cerebrospinal fluid helps boost cells that maintain brain function.

7/29/22 - The WORST FOODS That Cause Cognitive Decline! | Max Lugavere

7/28/22 - Age-dependent effects of blue light exposure on lifespan, neurodegeneration, and mitochondria physiology

7/24/22 - Stem cells, longevity and the final frontier

7/18/22 - The relationship between telomere length and beekeeping among Malaysians... Sweet

7/15/22 - Edits to a cholesterol gene could stop the biggest killer on earth

7/14/22 - Biological clocks or circadian rhythms and how they affect human health

7/13/22 - 5 unexpected health benefits of ditching the booze. From your hair to your brain, there are so many perks.

7/12/22 - Drinking just HALF of NHS safe weekly booze limit 'could leave you battling memory issues in old age

7/11/22 - Breakthrough study demonstrates the pivotal role of protein p62 in suppressing neurodegenerative disorders

7/10/22 - A recent study investigates whether body fat might influence cognitive performance

7/9/22 - Paleo vs Keto diet: which is better for longevity?

7/5/22 - Young Blood Plasma Reduces the Epigenetic Age of Rats by 54%

6/29/22 - Type 1 Diabetic Patients ‘Cured’ after Stem Cell Transplant

6/27/22 - Experimental Gene Therapy May Help Fight Inherited High Cholesterol

6/25/22 - Secrets of aging revealed in largest study on longevity, aging in reptiles and amphibians

6/21/22 - We regret to inform you that your choice of Deathday is no longer available

6/18/21 - Type 1 Diabetic Patients ‘Cured’ after Stem Cell Transplant

6/12/21 - Targeting cellular senescence to combat cancer and aging

6/8/22 - Not just a cousin of the naked mole-rat: Damaraland mole-rats offer unique insights into biomedicine

6/2/22 - The secret to a longer lifespan? Gene regulation holds a clue!

5/23/22 - New Research Finds Good Cholesterol Might Decrease Risk of Alzheimer's Disease

5/16/22 - Yale scientist explains why only 10-30% of our lifespan is estimated to be due to genetics

5/9/22 - Recent scientific advances raise the prospect of living longer – but ‘healthspan’ is just as important as lifespan

5/6/22 - Prehistoric viruses smuggled genes into our DNA... Some did good!

5/1/22 - Liz Parrish says... Longevity Research is an Economic Necessity.

4/26/22 - The science of anti-ageing from Aging Matters Magazine

4/24/22 - The evolution of long life in a world with pathogens

4/22/22 - Why Political Action Matters for the Rejuvenation Biotech Community

4/20/22 - Liz Parrish - Gene Therapy for Interstellar Travel

4/19/22 - Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity

4/18/22 - S-adenosyl-L-homocysteine extends lifespan through methionine restriction effects

4/16/22 - Resistance to chemical carcinogenesis induction via a dampened inflammatory response in naked mole-rats

4/14/22 - Autophagy: What You Should Know Before Starting Your Fast

4/7/22 - A Phase 1 Clinical Trial of Stem Cells for Alzheimer’s has positive effects

4/4/22 - Three videos made by older people from Canada, Jordan and Togo for the UN Decade of Healthy Ageing

3/30/22 - Scientists Identify The Optimal Number of Daily Steps For Longevity, And It's Not 10,000

3/24/22 - Science News - How gene therapy overcame high-profile failures

3/17/22 - Revel Pharmaceuticals Announces $8.4M Seed to Develop Repairing-Based Approaches to Reversing Aging

3/9/22 - Liz Parrish (Telomere patient zero) - latest interview about her quest To Reverse Aging

3/4/22 - Exercise Improves Cognition Depending on Type and Amount

2/23/22 - Newt Gingrich explains why Aging Research Is Key to Balancing the Budget

2/21/22 - Breast cancer breakthrough at Houston Methodist could double patients' odds of responding to treatment

2/18/22 - Caloric Restriction Promotes Rejuvenation in Human Trials

2/14/22 - Study Claims Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults

2/8/22 - Review of Clinical Trials Targeting Aging

2/1/22 - Creating Political Action to Increase Healthy Human Lifespan might be easier than expected

1/26/22 - How Organ Donors May Soon Be a Thing of the Past

1/24/22 - Blood proteins could be the key to a long and healthy life, study finds

1/21/22 - Altos Labs Announces they are investing Billions to develop Rejuvenation biotechnology

1/19/22 - Intermittent vs Prolonged fasting: which is better for weight loss... from Longevity Technology

1/14/22 - A long-term longitudinal study conducted over 20 years on the Effects of Metformin and Lifestyle on Mortality

1/10/22 - Drugs to Reverse Atherosclerosis from Repair Biotechnologies. A new way to deal with choesterol.

1/5/22 - The Science Behind Why We Age with Dr. David Sinclair

1/4/22 - Targeting the Molecular & Cellular Pillars of Human Aging with Exercise

1/3/22 - The hyperfunction theory: An emerging paradigm for the biology of aging

1/2/22 - Emerging rejuvenation strategies - Reducing the biological age

12/31/21 - The active grandparent hypothesis: Physical activity and the evolution of extended human healthspans and lifespans

12/20/21 - New Partnership Between Forever Healthy and Buck Institute to fund early-stage research to the clinic stage more quickly.

12/18/21 - NewLimit: A New Biotech Working on Epigenetic Aging, has raised more than $100 million so far.

12/16/21 - Modern Healthspan's 5 Part Video Interview with Dr Sandra Kaufmann of the Kaufmann Protocol   Part-1   Part-2   Part-3   Part-4    Part-5   Part-6

12/13/21 - Building a Universal Immunotherapy for Cancer. An improvement on previous techniques might quickly become a new standard of care.

12/11/21 - Late-Life Treatment Extends Nematode Lifespan by Two-Fold. This approach targets their version of the insulin pathway.

12/8/21 - A Licorice Derivative Restores Adipose Stem Cells in Vitro. The glycolysis pathway is central to its effects.

12/5/21 - Viagra Identified as a Candidate Drug for Alzheimer’s It was originally intended to treat hypertension.

12/2/21 - Using Young Stem Cells to Restore Old Stem Cells. The restored cells regain many of their youthful abilities.

11/30/21 - LifeSpan's Rejuvenation Roundup for November 2021

11/26/21 - Metformin Alleviates Cognitive Impairment in Long-Term Study. Patients who took it for more than six years showed positive outcomes

11/15/21 - Using Young Stem Cells to Restore Old Stem Cells but not all, of their youthful abilities

11/13/21 - Paralysed mice walk again after gel is injected into spinal cord

11/11/21 - New gene-editing technique offers scientists ability to 'turn on' enzymes that cause DNA base mutations

11/8/21 - Intranasal Gene Therapy for Dementia Demonstrates Cognitive Benefits

11/2/21 - A New Mechanism of Action of Rapamycin Identified

10/30/21 - Michael Gee, founder of the company Humanity claims, “Digital Markers Are the Future”

10/27/21 - Nature Aging review... Strategies for targeting senescent cells in human disease

10/21/21 - As tech titans invest in the quest to extend lives. Financial Times asks...Can we defeat Death?

10/13/21 - Longevity Foundation to Fund Geroscience Research with $1Billion

10/10/21 - Koschei the immortal and anti-aging drugs

10/6/21 - How to live longer: Five tips to reverse your biological age by three years in weeks

10/3/21 - FDA Approves First Human Trial for Potential CRISPR-Led HIV Cure

9/26/21 - Scientists Create Artificial Mitochondria that can Make Energy for Damaged Cells

9/24/21 - Our Brains’ Metabolism Changes as We Age - Many related to the microbiome

9/17/21 - COVID to Cancer - mRNA Treatment In Human Trials | BioNTech

9/13/21 - Epigenomic Rejuvenation for Restoring Bone Stem Cells

9/10/21 - Pterostilbene and Resveratrol Modulate the Gut Microbiota Influenced by Circadian Rhythm Dysregulation (chronic jet-lag)

9/1/21 - Jeff Bezos and Yuri Milner 'fund anti-aging start-up aimed at biological reprogramming to help humans live FOREVER

8/20/21 - Longevity Advice's updated list of Best and Essential anti-aging books

8/16/21 - The decision to approve a treatment for dementia has sparked considerable controversy.

7/27/21 - The Case for a Longevity Moonshot by BONNIE KAVOUSSI

7/25/21 - Evolution Won’t Stop Aging Any Time Soon, but Medicine Might

7/19/21 - Protein is an essential nutrient, but could too much speed up aging? Look at the science to see.

7/13/21 - Getting a Grip on Secular Changes: Age-Period-Cohort modeling of grip strength in the English Longitudinal Study of Ageing

7/5/21 - Gut Bacteria Strongly Influence the Aging Genome in Flies. Stress response and innate immunity genes most affected.

7/1/21 - New intranasal and injectable gene therapy for healthy life extension

6/29/21 - 6 Tips to Reduce Carcinogenic Barbecue Health Risks

6/23/21 - Silicon Valley Wants Dogs to Live Longer So Humans Can, Too

6/17/21 - Zoledronate extends healthspan and survival via the mevalonate pathway

6/16/21 - Milk, yogurt and cheese intake is positively associated with cognitive executive functions in older adults

6/15/21 - A systematic review of melatonin in retarding intervertebral disc ageing and degeneration

6/13/21 - Centenarians as models of healthy aging: Example of REST

6/6/21 - Studying the link between poor sleep quality and dementia. Sleep Should Be Part of a Longevity Strategy.

6/2/21 - Rapamycin Reduces Age-Related Hearing Loss in Mice. This well-known compound slows the degeneration of the related cells

6/2/21 - Oisín Announces $5 Million in that will go towards getting its senolytics ready for human clinical trials

6/1/21 - Heavy Alcohol Use Linked to Greater Epigenetic Age in Women

6/1/21 - Gene Therapy Preserves Memory in Alzheimer’s Mouse Model

5/29/21 - The human genome has finally been completely sequenced after 20 years!

5/28/21 - People aged 105 and over may live longer because they have more efficient DNA repair

5/27/21 - Glucosamine is a common supplement with some interesting data behind it

5/25/21 - Scientists Have Found a Way to Break the Limit of Human Longevity

5/21/21 - Living Forever with Dmitry Kaminskiy, Longevity Entrepreneur Video Interview

5/20/21 - Update on Human Trials of mTOR Inhibitors for Immune Aging

5/18/21 - Vitalik Donation for Longevity funding comes from the success of Ethereum.

5/14/21 - Why Quality Sleep Should Be Part of Your Longevity Strategy

5/10/21 - Whole-genome sequencing analysis of semi-supercentenarians

5/8/21 - Gene Therapy Today with Dr. Jason Williams and Liz Parrish

5/3/21 - Researchers Convert Astrocytes to Neurons in Vivo paveing the way for possible future brain regeneration therapies

5/1/21 - Longer lives is not longer decrepitude it's healthy longevity and independence... Here's why!

4/27/21 - Intermittent Fasting for Longevity: The Science Behind the Hype by Longevity Advice

4/25/21 - Hyper-Long Telomeres Give Non-Genetically Modified Mice Longer, Healthier Lives

4/22/21 - TEDx Talk by Max Lugavere "Dementia is preventable through lifestyle." 

4/22/21 - 5 Ways To Keep Long And Healthy Telomeres by Derek Mulch

4/19/21 - Mayo Clinic proof-of-concept study shows that removal of senescent cells in mice leads to improved cognitive responses

4/16/21 - Caloric Restriction for longevity as it stands today by Longevity Advice

4/11/21 - Lower Risk for Dementia Following Adult Tetanus, Diphtheria and Pertussis (Tdap) Vaccination

4/6/21 - Can AI help design longevity drugs in just one year?

4/3/21 - Organoids Might Replace Thyroid Hormone Therapy X10 Video from Lifespan news

3/26/21 - A Summary of Nicotinamide Mononucleotide the popular NMN supplement in the context of aging.

3/24/21 - Thyroid Organoids Created From Human Tissue may one day lead to thyroid replacement.

3/19/21 - RNA discoveries played a big role in the fast delivery of Covid Vaccines

3/18/21 - Is Increasing Human Lifespan Unnatural? Explore why healthy human longevity is likely a positive thing.

3/16/21 - Machine learning can identify cancerous cells by their acidity

3/14/21 - Quantum Dot Nanomedicine for Longevity Drugs accumulate in the liver, which can be a good thing.

3/11/21 - Longevity Advice Update on Human life Extension Possiblities

3/9/21 - Reprogramming Old Cells Young Again...How researchers are hitting the reset switch on aged cells

3/7/21 - The Dog Aging Project Is Ready for Takeoff

3/4/21 - DNA methylation-based age clocks: from age prediction to age reversion

3/2/21 - Measuring Age With a Blood borne Neural Protein

2/28/21 - New Horizons in the impact of frailty on pharmacokinetics: latest developments

2/25/21 - SIRT3 Replenishment Reverses Lung Fibrosis in Mice... Fibrosis is a balance, but aging puts its thumb on the scale.

2/20/21 - Optimism is associated with health benefits and improved survival among adults aged >65

2/13/21 - Found: A distinct organization of adaptive immunity in the long-lived blind mole rat

2/5/21 - Here's what underlies the mitochondrial stress response

1/30/21 - Nanoparticle injections into arthritic knees could slow cartilage loss

1/25/21 - 6 Best Biological Age Tests for 2021 by Rachel Burger of Longevity Advice

1/20/21 - Chinese scientists develop gene therapy which could delay ageing

1/18/21 - The Sheekey Science Show video on Fisetin Trials being tested for its senolytic effects in human beings

1/13/21 - Many of the beneficial long-term effects of exercise may be due to its senolytic effects

1/12/21 - Do we have to age? Biologist Andrew Steele weighs in on what can happen in this new decade!

1/11/21 - 6 Pros and Cons of Immortality: The Ethics of Life Extension from LongevityAdvice

1/7/21 - Senescent cells are promising targets to tackle age-related diseases

1/1/21 - New inhibitor gives researchers the ability to control programmed cell death in cultured human T cells

12/30/20 - Is exercise a senolytic medicine? A systematic review

12/22/20 - Artificial intelligence can do things in biotech that humans cannot

12/17/20 - MYSM1 Prolongs Lifespan by Regulating DNA Repair

12/16/20 - AKG promotes longevity via function as mimetic of caloric restriction and hormetin

12/8/20 - Media Circus Surrounds Hyperbaric Oxygen Study but it probably doesn't reverse human aging.

12/4/20 - Reversing Cellular Age in Mice Restores Vision

12/2/20 - CRISPR Successfully Deployed Against Two Cancer Types

12/1/20 - New drug could treat Alzheimer’s decades before symptoms begin

11/25/20 - CRISPR-based genome editing system treatment destroys cancer cells

11/22/20 - 14 Best Anti-Aging Research Journals for 2021

11/21/20 - Scientists Say They've Partially Reversed a Cellular Aging Process in Humans

11/20/20 - Deep Longevity Launches The First Longevity Medicine Course For Physicians

11/18/20 - Diluting aged blood improves cognition, reduces neuroinflammation, and spurs neurogenesis

11/16/20 - The role of senescent T cells in immunopathology

11/14/20 - Buyer beware of this $1 million gene therapy for aging

11/11/20 - Could Virtual Reality Improve Scientists’ Understanding of Cell Biology?

11/1/20 - Cartilage Regeneration Accomplished in Vitro

10/25/20 - CRISPR turns normal body fat into a type that burns energy

10/15/20 - Research team discovers mechanism that restores cell function after genome damage

10/6/20 - Data mining of human plasma proteins generates a multitude of highly predictive aging clocks

9/30/20 - Time-restricted feeding (TRF) for prevention of age-related vascular cognitive impairment

9/22/20 - Groundbreaking Alzheimer’s Study Administers First Dose

9/3/20 - Gut microbes could unlock the secret to healthy ageing

8/22/20 - Researchers find method to regrow cartilage in the joints

8/14/20 - The First Precision Gene Editing Tool for Mitochondrial DNA

8/12/20 - Flu, Pneumonia Vaccinations Tied to Lower Risk of Alzheimer's Dementia

8/8/20 - Frailty and Age-Related Immune Decline Reversed in Mice

8/4/20 - World-first gene therapy reverses Alzheimer's memory loss in mice

7/30/20 - A Single Molecule Can Regenerate the Gut Lining

7/27/20 - Genetics of extreme human longevity to guide drug discovery for healthy ageing

7/21/20 - New molecules reverse memory loss linked to depression and aging

7/13/20 - A Blood Factor Boosts Neurogenesis and Cognition

7/10/20 - Trimethylamine May be Involved in Vascular Aging by Steve Hill

7/6/20 - Edwina Rogers – Principles of Effective Advocacy for Longevity Therapies

6/27/20 - A Biomarker Based on Senescent Cell Secretions

6/19/20 - Science to Save the World – COVID-19 and Viral Pandemics

6/12/20 - Why is the novel coronavirus so deadly to the elderly? by SENS research

6/4/20 - How to Improve Your Health and Be a Longevity Activist by Elena Milova

5/24/20 - Study: Rapamycin has harmful effects when telomeres are short

5/17/20 - 101-Year-Old Man Who Survived Spanish Flu and World War 2, Now Beats Coronavirus Too

5/10/20 - Weight Loss and Mitochondrial Health with New Gene Therapy

4/30/20 - Instrumented measures of sedentary behavior and physical activity are associated with mortality
4/2/20 - Reversing Cellular Aging Takes Another Step Forward

3/30/20 - To Fight COVID-19, Hasten Recovery, And Boost The Economy, AI Scientist Proposes Making Older People Younger

3/28/20 - Stem Cell Therapy Successful in 7 COVID-19 Cases

3/24/20 - Scientists investigate why females live longer than males

3/20/20 - Systemic immunity protects the mind: Can immune checkpoint blockade combat Alzheimer’s disease?

3/14/20 - Reversing Cellular Aging Takes Another Step Forward

3/9/20 - First Patient Receives In Vivo CRISPR Editing

3/7/20 - Plant-based relatives of cholesterol could give boost to gene therapy

3/4/20 - Seniors Who Walk For 30 Minutes Daily Cut Risk Of Death From Any Cause

3/1/20 - 114 year-old cells converted to pluripotent stem cells

2/28/20 - CRISPR Edited Immune Cells Successful in First U.S. Clinical Trial

2/24/20 - King’s College in London to Test Senolytic for Heart

2/20/20 - The ultra-rich are investing in companies trying to reverse aging.

2/6/20 - Age Reversal Network - Bill Faloon Update - Vitality in Aging Research Group

1/31/20 - Fish that can repair their OWN HEART offer clues for millions

1/30/20 - Potential way to halt blinding macular degeneration identified

1/27/20 - AI Driven Biomarkers Could Help Prevent Age-Related Diseases

1/23/20 - 10 reasons to build the human genome from scratch

1/18/20 - Pathways that extend lifespan by 500 percent identified

1/13/20 - Geriatrician John Newman explains how science could intervene in the aging process

1/8/20 - These 'Blue Zones' Foods May Help You Live Longer—Wine and Bread Included

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Posts back to the first in 2018